Reliability of cystatin C in estimating renal function in rugby players

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Cystatin C and renal function in pediatric renal transplant recipients

In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation be...

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Cystatin C, renal function, and cardiovascular risk.

Because all the patients had chronic kidney disease (CKD) (GFR <55 mL/min per 1.73 m 2 ), this study cannot be used to assert that cystatin C is definitively better than creatinine for detecting stage 3 kidney disease (GFR <60 mL/min per 1.73 m 2 ). Regarding the study methods, the authors do not mention when cystatin C was measured in the frozen samples. Were the samples measured retrospective...

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Cystatin C and renal function in pediatric kidney transplant recipients.

In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation be...

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Cystatin C: a marker of renal function or something more?

Over the past decade, we have come to appreciate that individuals with even moderately reduced renal function are at increased risk for cardiovascular morbidity and mortality. There is no consensus, however, on how renal function should be measured. The most precise and accurate methods (such as inulin clearance) are impractical in the clinical setting and for larger research studies. Serum cre...

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ژورنال

عنوان ژورنال: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

سال: 2009

ISSN: 0004-5632,1758-1001

DOI: 10.1258/acb.2009.009135